模板:PBB/920

{{GNF_Protein_box
 | Name = CD4 molecule<br>CD4分子
 | image = T Cell Surface Glycoprotein CD4 - PDB 1CDH.jpg
 | image_source = Crystallographic structure of the  V-set and C2 domains of human CD4.<ref name="pmid8075984">{{PDB|1cdh}}; {{cite journal | author = Ryu SE, Truneh A, Sweet RW, Hendrickson WA | title = Structures of an HIV and MHC binding fragment from human CD4 as refined in two crystal lattices | journal = Structure | volume = 2 | issue = 1 | pages = 59–74 | date =January 1994 | month =  | pmid = 8075984 | doi = | url = | issn = }}</ref>
 | PDB = {{PDB2|1CDH}}, {{PDB2|1CDI}}, {{PDB2|1CDJ}}, {{PDB2|1CDU}}, {{PDB2|1CDY}}, {{PDB2|1G9M}}, {{PDB2|1G9N}}, {{PDB2|1GC1}}, {{PDB2|1JL4}}, {{PDB2|1Q68}}, {{PDB2|1RZJ}}, {{PDB2|1RZK}}, {{PDB2|1WBR}}, {{PDB2|1WIO}}, {{PDB2|1WIP}}, {{PDB2|1WIQ}}, {{PDB2|2B4C}}, {{PDB2|2JKR}}, {{PDB2|2JKT}}, {{PDB2|2KLU}}, {{PDB2|2NXY}}, {{PDB2|2NXZ}}, {{PDB2|2NY0}}, {{PDB2|2NY1}}, {{PDB2|2NY2}}, {{PDB2|2NY3}}, {{PDB2|2NY4}}, {{PDB2|2NY5}}, {{PDB2|2NY6}}, {{PDB2|2QAD}}, {{PDB2|3B71}}, {{PDB2|3CD4}}, {{PDB2|3JWD}}, {{PDB2|3JWO}}, {{PDB2|3LQA}}, {{PDB2|3O2D}}, {{PDB2|3S4S}}, {{PDB2|3S5L}}, {{PDB2|3T0E}}, {{PDB2|4JM2}}
 | HGNCid = 1678
 | MGIid = 88335
 | Symbol = CD4
 | AltSymbols =; CD4mut
 | IUPHAR = 
 | ChEMBL = 2754
 | OMIM = 186940
 | ECnumber = 
 | Homologene = 513
 | GeneAtlas_image1 = PBB_GE_CD4_203547_at_tn.png
 | GeneAtlas_image2 = 
 | GeneAtlas_image3 = 
 | Protein_domain_image = 
 | Function = {{GNF_GO|id=GO:0001948 |text = glycoprotein binding}} {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004888 |text = transmembrane signaling receptor activity}} {{GNF_GO|id=GO:0005201 |text = extracellular matrix structural constituent}} {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0008270 |text = zinc ion binding}} {{GNF_GO|id=GO:0015026 |text = coreceptor activity}} {{GNF_GO|id=GO:0019899 |text = enzyme binding}} {{GNF_GO|id=GO:0019901 |text = protein kinase binding}} {{GNF_GO|id=GO:0042289 |text = MHC class II protein binding}} {{GNF_GO|id=GO:0042803 |text = protein homodimerization activity}}
 | Component = {{GNF_GO|id=GO:0005769 |text = early endosome}} {{GNF_GO|id=GO:0005788 |text = endoplasmic reticulum lumen}} {{GNF_GO|id=GO:0005789 |text = endoplasmic reticulum membrane}} {{GNF_GO|id=GO:0005886 |text = plasma membrane}} {{GNF_GO|id=GO:0009897 |text = external side of plasma membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}} {{GNF_GO|id=GO:0042101 |text = T cell receptor complex}} {{GNF_GO|id=GO:0045121 |text = membrane raft}}
 | Process = {{GNF_GO|id=GO:0001816 |text = cytokine production}} {{GNF_GO|id=GO:0006948 |text = induction by virus of host cell-cell fusion}} {{GNF_GO|id=GO:0006955 |text = immune response}} {{GNF_GO|id=GO:0007155 |text = cell adhesion}} {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007166 |text = cell surface receptor signaling pathway}} {{GNF_GO|id=GO:0007167 |text = enzyme linked receptor protein signaling pathway}} {{GNF_GO|id=GO:0007169 |text = transmembrane receptor protein tyrosine kinase signaling pathway}} {{GNF_GO|id=GO:0016032 |text = viral reproduction}} {{GNF_GO|id=GO:0022415 |text = viral reproductive process}} {{GNF_GO|id=GO:0030217 |text = T cell differentiation}} {{GNF_GO|id=GO:0030260 |text = entry into host cell}} {{GNF_GO|id=GO:0031295 |text = T cell costimulation}} {{GNF_GO|id=GO:0032507 |text = maintenance of protein location in cell}} {{GNF_GO|id=GO:0045058 |text = T cell selection}} {{GNF_GO|id=GO:0045086 |text = positive regulation of interleukin-2 biosynthetic process}} {{GNF_GO|id=GO:0045087 |text = innate immune response}} {{GNF_GO|id=GO:0045234 |text = protein palmitoleylation}} {{GNF_GO|id=GO:0045860 |text = positive regulation of protein kinase activity}} {{GNF_GO|id=GO:0050690 |text = regulation of defense response to virus by virus}} {{GNF_GO|id=GO:0050731 |text = positive regulation of peptidyl-tyrosine phosphorylation}} {{GNF_GO|id=GO:0050829 |text = defense response to Gram-negative bacterium}} {{GNF_GO|id=GO:0050850 |text = positive regulation of calcium-mediated signaling}} {{GNF_GO|id=GO:0050852 |text = T cell receptor signaling pathway}} {{GNF_GO|id=GO:0050863 |text = regulation of T cell activation}}
 | Hs_EntrezGene = 920
 | Hs_Ensembl = ENSG00000010610
 | Hs_RefseqmRNA = NM_000616
 | Hs_RefseqProtein = NP_000607
 | Hs_GenLoc_db = hg19
 | Hs_GenLoc_chr = 12
 | Hs_GenLoc_start = 6896024
 | Hs_GenLoc_end = 6929974
 | Hs_Uniprot = P01730
 | Mm_EntrezGene = 12504
 | Mm_Ensembl = ENSMUSG00000023274
 | Mm_RefseqmRNA = NM_013488
 | Mm_RefseqProtein = NP_038516
 | Mm_GenLoc_db = 
 | Mm_GenLoc_chr = 6
 | Mm_GenLoc_start = 124864692
 | Mm_GenLoc_end = 124888221
 | Mm_Uniprot = P06332
 | path = PBB/920
}}<noinclude>

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